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Zeitschriftenbeiträge:

Forsdahl Guro, T. Geisendorfer, G. Gmeiner:
"Quantification and Stability of Salbutamol in Human Urine";
Journal of Separation Science, Vol. 27 (2004), Nr. 1-2; S. 110 - 114.



Kurzfassung:
A sensitive method for the quantification of free salbutamol in human urine is described. Sample clean up is performed using SPE an a mixed phase extraction column. Derivatisation is performed with N-methyl-N-trimethylsilyltrifluoroacetamide (MSTFA) and the extract is analysed by GC-MS. The method was found to be suitable for use in the doping field, where a cut-off limit of 1 ILg salbutamol/mL urine is set by the International Olympic Committee (IOC) and approved by the World Anti-Doping Agency (WADA). Above that value a doping violation occurs. In addition, the stability of salbutamol in human urine has been evaluated.

Schlagworte:
salbutamol, gas chromatography, mass spectrometry, solid phase extraction, urine, doping

Erstellt aus der Publikationsdatenbank des AIT Austrian Institute of Technology.